Our data suggest that local IgA antibodies might have a stronger discriminative value than local IgG, as IgA presence in the vaginal mucosa was associated with tubal pathology and history of Chlamydia infection in women in the fertility clinic and it correlated to current Chlamydia infection and to the presence of IgG in serum in the group of women in the STI clinic. The gene discussed is CD79A; the disease is chlamydia infectious disease.