IL6 and Cachexia: These patients showed a wasting syndrome with a statistically lean body mass loss (P = .005), declined total physical activity, increased resting energy expenditure (P = .019), and increased inflammatory cytokines and inflammatory mediators (C-reactive protein (C-RP), P = .09 and IL-6, P = .08)) during concomitant CT-RT even though there were no significant differences in energy intake or calorie/nitrogen ratio from pretreatment to posttreatment.