TP53 and glioblastoma: Finally, the ability of compounds 1 and 7 to modulate the cellular parameters which could be activated by both TSPO and p53, i.e. Δψm dissipation and cell viability, was examined in GBM cells and compared with the effects elicited by incubation with the single target standard ligands, Nutlin-3 and PK11195, used alone or in combination.