MUC1 and gastric cardia adenocarcinoma: In 2010, Abnet et al. [6] conducted a GWAS on gastric cardia adenocarcinoma (GCA) and identified a statistically significant SNP of rs4072037 in mucin1 (MUC1) gene, which located at 1q22 is a synonymous SNP in the second exon of MUC1, pointing intricate role of MUC1 in malignancy.