Compared to the sham-operated group, GAP-43 and TH mRNA levels in the MI-control group were significantly increased at the infarcted border (∼2 mm around the infarcted area) and in the non-infarcted LV (>2 cm away from the infarcted scar) at 8 wk time point after MI (p<0.01 and p<0.05 respectively, Table 2). This evidence concerns the gene GAP43 and myocardial infarction.