Thus, both with regard to HLA class I and LMP10 expression in relation to survival, there were differences between HPV-positive and HPV-negative tumours, although these were more pronounced for HLA class I. Notably, as demonstrated by the multivariate analysis in Table 4, expression of LMP10 and HLA class I were independent predictors of survival for both HPV-positive and HPV-negative tumours. The gene discussed is PSMB10; the disease is neoplasm.