Thus, only applying hCMs for conventional in vitro screening is not enough to get more precise prediction of arrhythmia occurrence, whereas, the combination of hCMs with the new approach of spatiotemporal measurement of temporal STVFPD and spatial STVConductance give us an potential of global predictive arrhythmic cardiotoxicity measurement beyond existent hERG and APD/QT assays as a cell network assay to reach to the quasi in vivo screening. Here, KCNH2 is linked to Arrhythmia.