Microarray data from Radich et al.1 revealed that EVI1 in the whole BM is upregulated in advanced phase (accelerated phase (AP) and BC) of CML compared with CML-CP, possibly implying the limited EVI1 in CML-CP stem cells and the extended EVI1 in BM of CML-AP and CML-BC (Figure 1c). The gene discussed is MECOM; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.