As authentic Evi1 targets,22,33,34 such as Gata2, Pten and Pbx1, showed no difference in expression levels between Evi1-high and Evi1-low CML cells (data not shown), the further exploration of CML-specific Evi1 targets would be warranted. This evidence concerns the gene RUNX1 and chronic myelogenous leukemia, BCR-ABL1 positive.