As CML-CP cells could be distinguished by their positive expression of BCR–ABL from normal BM cells, it was revealed that, among CML-CP cells, CD34+CD38–CD90+ cells showed lower Ct values of EVI1 than CD34+CD38+ cells or CD34–CD33+ cells intraindividually, implying the highest EVI1 in CML-CP stem cells (Figure 1a). The gene discussed is CD33; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.