54 In our CML-BC model, HOXA9 showed no difference between Evi1-high and Evi1-low LK cells, eliminating the possible dependence of Evi1-high cells on NUP98–HOXA9 (Supplementary Figure S4b). The gene discussed is NUP98; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.