INS and Insulin resistance: Another possibility as to why insulin resistance was not observed is that mice fed with TEN had a significant increase of hepatic omega‐3 PUFA (i.e. eicosapentanoic acid, Table 5) which are anti‐inflammatory and can improve insulin action (Kalupahana et al. 2011; Gillies et al. 2012; Rius et al. 2012).