To determine which iPLA2 isoform was involved in T. cruzi‐mediated arachidonic acid and PAF production, we pretreated HCAEC with (R)‐ or (S)‐BEL to inhibit iPLA2γ or iPLA2β selectively (Jenkins et al. 2002) prior to infection with T. cruzi. This evidence concerns the gene PNPLA8 and infection.