WD elicits increased Fos expression in the AP (Gottlieb et al. 2006, and AP lesions attenuate hypertension secondary to angiotensin II infusion (Fink et al. 1987a as well as the increase in vasopressin triggered by acute systemic increases in osmolality (Huang et al. 2000. The gene discussed is AGT; the disease is Hypertension.