AKT1 and pulmonary arterial hypertension: Recent study has shown the Akt/mTOR pathway to be important to PASMC proliferation in experimental animal models of PAH and hypoxia‐induced PASMC proliferation in vitro (Humar et al. 2002; Paddenberg et al. 2007; Agard et al. 2009; Houssaini et al. 2013).