While no significant differences in any marker between DLE+/SLE− and DLE+/SLE+ skin were found, there were trends towards stronger immunostaining of CD3, CD4, CD8, CD20, CD68, CXCR3, CXCL10, and TIA-1 in most areas of DLE+/SLE− skin compared with DLE+/SLE+ skin. This evidence concerns the gene TIA1 and systemic lupus erythematosus.