FLT3 and acute myeloid leukemia: FMS-like tyrosinekinase 3 (FLT3)—a new member of the receptor tyrosinekinase (RTK) III subfamily—was originally identifiedin hematopoietic stem/progenitor cells and is importantfor normal lymphohematopoietic stem cell function [4].FLT3 is aberrantly expressed in the most of AML patients.The FLT3 gene is located on chromosome 13 (13q12) [5].To date, 2 distinct types of FLT3 gene mutations have beenidentified in AML cases: 1.