NTRK1 and acute myeloid leukemia: Leukemia is classified based on the presence of specificcytogenetic abnormalities, as well as the French-American-British (FAB) classification of leukemic cells [2].A number of studies suggest that c-kit—a member of thetype III receptor tyrosine kinase (RTK) family is importantfor the development of a range of cells including hematopoieticcells, and plays a role in leukemogenesis—[3].High-level expression of c-kit has been reported in 60%-80% of acute myeloid leukemia (AML ) patients [4,5] andpoint mutation of c-kit has been observed in 33.35%45%of AML patients [6].