TP53 and cancer: p53 expression was higher when cancer NSCLC cells were treated with anti-miR-150 expression vector that indicates that the upregulation of p53 contributes to cancer growth [86]. miR-150 targets p53 in NSCLC cell lines (SPCA-1, A549, HCC827, 95-D, and BEAS-2B), which in turn regulates the expression of various tumor-suppressor miRNAs participating in cell cycle progression [85].