CASP3 and lung cancer: Mitochondrial/postmitochondrial steps of the intrinsic pathway of apoptosis, including Bax oligomerization, mitochondrial transmembrane potential dissipation, and the proteolytic maturation of caspase-9 and caspase-3, were modulated by pre-miR-181a and pre-miR-630 in A549 lung cancer cell line [66].