Interestingly, the majority of P. falciparum-inducible IL-10-producing PBMCs following febrile malaria were CD3+CD4+ T cells (Figure 3B; mean 53.1%, 95%CI: 44.8–61.5) and most of these were CD25+FOXP3− (Figure 3B; mean 78.8%, 95%CI: 72.2–85.5), while FOXP3+CD4+ T cells (regulatory T cells) represented only a small percentage of IL-10-producing T cells. This evidence concerns the gene CD4 and malaria.