SL exposure also induced changes in the expression of genes involved in metabolic functions in tumor and stem cells (ALDH1B1, ABCB1, SLC3A2, SLC44A2, SLC31A2, SLC7A11, CYP24A1, PTGS2/COX2, PPRC1), cytokines (CCL3L3, GDF15) and growth and differentiation factors (PGF, TGFBR11 and FOXD1). The gene discussed is PTGS2; the disease is neoplasm.