CCL2 and focal segmental glomerulosclerosis: Because macrophage infiltration is a common finding in FSGS experimental models (Diamond and Pesek-Diamond, 1991; Ohtaka et al., 2002; Pereira et al., 2011), we evaluated the role of B2RBK blockage on the renal expression of macrophage-related proteins (Fig. 3D–F) and also on the expression of monocyte chemoattractant protein 1 (MCP-1, also known as CCL2) mRNA (supplementary material Fig. S3A).