By directly targeting postprandial hyperglycemia rather than acting as a “conventional” hypoglycemic agent, acarbose is not only aiming at the most inappropriately elevated and longest lasting component of aberrant diurnal glucose metabolism in diabetic individuals, but is also suitable for combination therapy with all other blood glucose lowering agents such as metformin, sulfonylureas, DPP4 inhibitors, GLP-1 agonists, and insulin [11,16]. This evidence concerns the gene GCG and Hyperglycemia.