The frequency of circulating Lin-HLA-DR-CD33+CD11b+CD15+ subset was significantly higher in PC patients compared with HDs (8.86% versus 1.33%; P = 0.0003) but was not statistically higher in comparison with CPs (P = 0.54) as shown in Figure 1(b). The gene discussed is FUT4; the disease is pachyonychia congenita.