Tumour infiltrating macrophages, also indicated as TAMs (Figure 2(a)), derive from circulating monocytic precursors and are recruited to tumour sites by several molecules, such as the chemokines CCL2 and CCL5, VEGF, TGF-β, and colony stimulating factors (GM-CSF and M-CSF) [53, 55]. Here, TGFB1 is linked to neoplasm.