CD4 and neoplasm: The results showed that, in contrast to peripheral-derived γδ T cells, tumor-activated γδ T cells induced significantly higher proliferation of CD4+ T cells (Figures 2(a) and 2(b); n = 3, P < 0.01) and CD8+ T cells (Figures 2(c) and 2(d); n = 3, P < 0.01) in a number-dependent pattern, as assessed by the reduction in CFSE signals.