CD8A and tuberculosis: Given that expression of CD127, the IL-7 receptor α chain, is important for T cell survival and homeostasis [68], [69], and that expression of Bcl-2 is important for preventing apoptosis [62], the relatively lower levels of CD127 and Bcl-2 expression on CFP-10/ESAT-6-specific CD8 T cells in patients treated for TB, compared with individuals with LTBI, suggests antigen-specific memory CD8 T cells may remain more prone to cell death in patients following successful treatment of TB disease.