Cell growth experiments carried out during 24 h exposure to salinomycin, TRAIL and the combination of both in GBM cells preincubated with zVADfmk confirmed that the caspase inhibitor fully suppressed the cell death induced by co-treatment with salinomycin and TRAIL in U251 cells, but not in T98G and U87MG cells (Fig. 4B). This evidence concerns the gene TNFSF10 and glioblastoma.