ANXA5 and glioblastoma: In fact, salinomycin-sensitive glioblastoma cell lines did not show caspase activation following salinomycin treatment; furthermore, zVAD, a pan-caspase inhibitor was unable to protect glioblastoma cells from salinomycin-induced cell death; finally, salinomycin-treated cells fail to bind annexin V, a typical feature of apoptotic cells.