Given that the structure of the oligosaccharides and their functions have only been partly unveiled, further studies are required to elucidate molecular mechanisms underlying the effects of N-glycans on the functions of CD147 in cancer biology, to disclose the distinct oligosaccharides structures on its three glycosylation sites and their respective functions and to confirm whether aberrant glycans on CD147 could be used as a marker to predict clinical prognosis of cancer or drug resistant response of cancer therapy. This evidence concerns the gene BSG and cancer.