The inhibitory mechanism of Panax ginseng on asthma parameters in mice is reflected in: PG restoring the expression of estramustine binding protein (EMBP), Mucin-5 subtype AC (Muc5ac), CD40, and CD40L, as well as the mRNA and protein levels of interleukin (IL)-1β, IL-4, IL-5, and tumor necrosis factor (TNF)-α. The gene discussed is IL5; the disease is asthma.