The correlations between BRF2 protein immunoreactivity and E-Cadherin, N-Cadherin, or snail were analyzed by Mann-Whitney U test, and the result also showed that high expression of BRF2 correlated with a loss of E-Cadherin expression (P = 0.048) and anomalous positivity of N-Cadherin (P = 0.045); we also found such a trend in the correlation between high expression of BRF2 and positivity of snail in clinical NSCLC samples, despite the fact that the statistical significance was not reached. Here, BRF2 is linked to non-small cell lung carcinoma.