SETD4 and breast carcinoma: As shown in Figure 2A, the expression of SETD4 was elevated in the HCC-1954, SKBR-3, MDA-MB 231 and MDA-MB 436 cell lines compared with the control HCC-1954-BL cell line, a lymphoblast cell line isolated from the same individual from who the HCC-1954 breast cancer cells were isolated (p<0.001).