PANX2 and autism: From Table 2, four genes LASS3, PANX2, SLC15A4, and ENO2 were selected for further study based on the following concerns: (1) significant difference of methylation status among these genes that were identified with MeDIP array in five pairs of autism-control cases; (2) gene function(s), more importantly, their potential roles that had been reported previously in the development of autism [1, 30]; and (3) their expression in the peripheral blood, which might be a potential candidate of biomarker for assisting clinical recognition and early detection of autism.