GPT and cryohydrocytosis: In our study, the univariate and multivariate analyses showed that HexCer (d18∶1/22∶0) correlated with alteration of hepatic inflammation grade in CHC, and verified that HexCer (d18∶1/22∶0) had an independent relationship with hepatic necroinflammation (G≥2) after adjusting for other factors, especially in CHC patients with normal ALT level.