The CAP system for specific serum IgE testing has higher sensitivity than RAST tests with comparable specificity; and a recent study has suggested that both SPTs and specific IgE measurement by the (ImmunoCAP) system should be used in diagnoses of fungal allergy, due to discordance in test results in around a quarter of severe asthma patients [43]. The gene discussed is IGHE; the disease is asthma.