Before presenting the findings of the association of DNA methylation changes with asthma status transitions, we focus on the 4 CpG sites included in the selected models and first discuss the stability of DNA methylation at these CpG sites (cg12405139 [GATA3], cg09791102 [IL4R], cg26937798 [IL4R], and cg23943829 [IL4]) between ages 10 and 18. This evidence concerns the gene IL4 and asthma.