As described in Figure 5, we found that target genes involved 47 significant pathways in total, including (−Lg P ≥ 5) MAPK signaling pathway, glioma, neurotrophin signaling pathway, axon guidance, ErbB signaling pathway and chronic myeloid leukemia, pathways in cancer, and non-small-cell lung cancer. Here, BDNF is linked to chronic myelogenous leukemia, BCR-ABL1 positive.