The functional deficits gradually recovered with time; however, the recovery in Plg-/- mice was significantly worse than in Plg+/+ mice post-stroke, assessed in both foot-fault test (A, p<0.01 at day 21 and p<0.001 at day 28) and single pellet reaching test (B, p<0.01 at day 21 and 28). This evidence concerns the gene PLG and Stroke.