BMP7 and Miyoshi myopathy: For NPCs induction, high doses of BMP7 (150 ng/ml) and FGF2 (50 ng/ml) were added for the specification of NPCs from IM cells because ureteric bud-secreting factors BMP7 and FGF2 have been known as the most important signaling factors to proliferate and sustain self-renewal potential of renal progenitor cells in MM [12], [16].