AGT and cardiac hypertrophy: In this study, we first produced a rat model of myocardial hypertrophy using the TAAC operation and then an in vitro cardiomyocytes hypertrophic model using Ang II treatment, ATG9A cDNA transfection, or lentiviral infection of miR-34a inhibitor, or miR-34a mimics, or ATG9A siRNA.