AGT and infection: Both Ang II treatment and transfection of ATG9A cDNA induced ATG9A expression in cardiomyocytes and upregulated levels of ANP and β-MHC mRNA, whereas the negative control or Ang II treatment plus ATG9A siRNA infection reduced the levels of ANP and β-MHC mRNA in cardiomyocytes compared to Ang II treatment plus the negative control (Figs. 3A and 7A).