However, coincubation of 10 mmol/L NAC with DCA and/or ADM in the HCC-LM3 cells resulted in significantly lower intracellular ROS levels compared with the respective treatment groups without NAC, indicating that the oxidative stress induced by DCA and/or ADM was attenuated with exposure to NAC (Fig. 3A). This evidence concerns the gene ADM and hepatocellular carcinoma.