CEACAM5 and neoplasm: Pre-specified multivariate analysis of time to death from all causes for patients in stages I-III, including the covariates gender, age (per 10 years), stage, tumour localisation, adjuvant chemotherapy, levels of CEA and total Cat X and interactions terms between chemotherapy and the biomarkers identified a subgroup of patients with a significant association with the outcome of the disease, as shown in Table 3.