IFNG and neoplasm: Notably, expression of IFN-γ was similar in the tumor and adjacent tissue (Figure 3A), indicating that a higher production of IFN-γ by immune cells in the tumor did not contribute to the increased mRNA levels of STAT1 and IRF-1.We cannot rule out that the increased levels of STAT1 mRNA STAT1 and IRF-1 in the tumor are the result of higher abundance of immune cells expressing these genes in the tumor.