The epithelial trait marker, E-cadherin, was upregulated whereas at the same time N-cadherin and Snail which belonged to specific mesenchymal biomarker were correspondingly decreased in a different level, suggesting that restoration of let-7g could alleviate the EMT extent that is crucial event in HCC progression and recurrence [22]. This evidence concerns the gene CDH1 and hepatocellular carcinoma.