EDN1 and ischemia: Four weeks after ischemia the ET-1 levels of the treatment groups were decreased compared to model group (FS: 166.15 ± 9.01 ng/L, SNT-LD: 166.74 ± 7.70 ng/L, and SNT-HD: 158.49 ± 9.97 ng/L versus model group: 171.09 ± 13.17 ng/L).