MT-ND2 and age-related macular degeneration: At the Marshfield/Essentia Health site, a genetic risk score for age-related macular degeneration (AMD) is calculated based on five variants in CFH, one variant in ARMS-2, one variant in C3 and one variant in ND2. Individuals (n = 100) attending optometry clinics are genotyped for these variants (Haines et al., 2005) and a genetic risk score is calculated and incorporated into the EHR by optometrists.