These include genes associated with long QT syndrome genes (KCNH2 and SCN5A), malignant hyperthermia (RYR1 and CACNA1S), hypercholesterolemia (LDLR), and catecholaminergic polymorphic ventricular tachycardia (RYR2). This evidence concerns the gene RYR1 and Malignant hyperthermia.