Silencing of DNMT1 restores to normal eNOS mRNA levels in IUGR HUAEC and HUVEC, and this effect is not observed on arginase-2 expression where it further increases its expression in IUGR HUVEC, without any effect in IUGR HUAEC (Krause et al., 2013). Here, DNMT1 is linked to fetal growth restriction.