Several pro-apoptotic proteins are increased following perinatal asphyxia, including B-cell lymphoma-2 (Bcl-2) associated X (BAX), and Bcl-2 associated death (BAD) factors, but also anti-apoptotic proteins, including Bcl-2, extracellular signal-regulated kinase 2 (ERK2), and basic fibroblast growth factor (bFGF) (Morales et al., 2008). This evidence concerns the gene MAPK1 and asphyxia.