However, we also determined that initial adequate antibiotic use, low physiologic scores for APACHE II, SOFA, and SAPS II at days 1 and 3, and a large day 3 : day 1 value for the APACHE II and SAPS II scores may result in a low ICU mortality rate in patients with severe pneumonia and ARDS. The gene discussed is BTBD8; the disease is susceptibility to pneumonia measurement.