It is well established that 1O2 is the major ROS generated under HL conditions (Triantaphylidès et al., 2008; Triantaphylidès and Havaux, 2009) and, consequently, the activation of defence responses under HL conditions ought to share a set of 1O2-responsive transcripts with the flu mutant family. This evidence concerns the gene ZMYND10 and Hodgkins lymphoma.