The presence of the ADH1C rs1614972 CG or GG genotype was also associated with an increased risk of ESCC (OR = 1.70; 95% CI = 1.26–2.30 or OR = 5.50; 95% CI = 1.21–25.0, respectively) compared with the absence of such a genotype. The gene discussed is ADH1C; the disease is esophageal squamous cell carcinoma.