TKT and gastric carcinoma: Thus, by testing the efficacy in xenografted model of human orthotopic gastric carcinomas with disseminated metastasis and the safety in immunocompetent, permissive Syrian hamsters, this study suggests that the M7 and M8 viruses are safer and more efficacious than Adv-TK and suggests a potential clinical application for these viruses in cancer gene therapy.