In AC, mutations were found in tumor suppressors SMARCA4/BRG1 (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin) and ARID1A (AT-rich interaction domain 1A) – both members of the SWI/SNF complex, in 8% and 10% of tumors, respectively [2]. The gene discussed is SMARCA4; the disease is neoplasm.